Are the Individual Inputs on the Device Isolated from Each Other?

No. All inputs on every product share a common ground internally, and that ground is also shared with the USB connection, and thus the host PC.

For more information about isolation, please see this article: What should I do to avoid accidental damage to the device?

For digital channel-to-channel isolation, we suggest considering this eval kit from SI Labs:

For isolation from the host PC, we suggest considering this USB 2.0 high-speed isolator:

Note: There are no USB 3.0 isolators on the market yet as far as we are aware.

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